Hyperkeratotic dermis of anal canal

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These fissures can be accompanied by mucosal flaps, which can be large and shaped like elephant ears. This may account for the fact that anal cancers tend to present in advanced stages. The one landmark to which all definitions and problems need to be related is the dentate line , also known as the pectinate line , which is the single, reproducible, constant, but wavy line that runs circumferentially around the anal mucosa and which is easily visible in the opened, resected specimen Fig. The ATZ with its mixed epithelial lining is considered important in maintaining fecal continence. The first is the internal anal sphincter, which is a continuation and modification of the circular muscle of the rectum. The pattern of lymphatic drainage of the anal canal plays a crucial role in tumor spread. Unfortunately, there is virtually no literature on these lesions, so we have no clue as to their behavior and etiology.
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Epidermal and Hair Follicle Tumors - Integumentary System - Merck Veterinary Manual

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Vulval adenosis associated with toxic epidermal necrolysis. Apocrine ductular adenomas are less common. Influenza virus vaccine, quadrivalent IIV4 , split virus, preservative free, 0. The second presentation is cutaneous papillomas , which are indistinguishable from the warts that develop on or around mucous membranes.
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Hyperkeratotic dermis of anal canal Lossing virginity pussy

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